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Test Code UBT Helicobacter pylori Breath Test

Ordering Guidance

An alternative test for the diagnosis of active Helicobacter pylori infection in patients is the HPFRP / Helicobacter pylori with Clarithromycin Resistance Prediction, Molecular Detection, PCR, Feces, which requires a different collection.

Specimen Required

Patient Preparation:

1. Patient should be fasting for 1 hour.

2. Patients should not have taken bismuth/Tritec, antimicrobials, proton-pump inhibitors (eg, Prilosec, Prevacid, Aciphex, Protonix, and Nexium) or bismuth preparations (eg, Pepto-Bismol) for 2 weeks prior to testing. If these instructions are not followed, test results may be inaccurate. Do not administer this test.

3. Histamine 2-receptor antagonists (H2RA) such as Pepcid, Tagamet, Axid, or Zantac should be discontinued for 24 to 48 hours before the BreathTek UBT test is administered. If these instructions are not followed, test results may be inaccurate. Do not administer this test.

4. Carafate (sucralfate) does not interfere with the test. Use of antacids does not affect the accuracy of this assay.

Supplies: H. Pylori Breath Kit - Meridian Breath ID (T906: fees apply)

Collection Instructions:

1. Do not collect if patient is younger than 3 years of age.

2. Follow instructions included with kit.

3. Mixing the (13)C-Urea Tablet

a. Dissolve the Citrica and the (13)C-enriched urea tablet in 150 to 200 mL (5.1 to 6.8 oz.) of tap water in the provided drinking cup.

b. Close the lid firmly using both hands. Place fingers over lid and shake thoroughly for a few minutes, until the Citrica Powder and the urea tablet are completely dissolved.

Note: Tiny particles may remain visible after thorough mixing. However, if more substantial particulate matter is still present after five minutes of mixing, discard the solution and repeat the procedure with a new kit.


If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Infectious Disease Serology Test Request (T916)

-Gastroenterology and Hepatology Client Test Request (T728)

-Microbiology Test Request (T732)

Useful For

Diagnostic testing for Helicobacter pylori infection in patients suspected to have active H pylori infection


Monitoring response to therapy


This test is not appropriate for asymptomatic people.

Testing Algorithm

For more information see Helicobacter pylori Diagnostic Algorithm.

Method Name

Qualitative Spectrophotometry (SP)

Reporting Name

H. pylori C Urea Breath Test

Specimen Type


Specimen Minimum Volume

Bag of ’’breath’’ must be full

Specimen Stability Information

Specimen Type Temperature Time Special Container
Breath Ambient 14 days BREATH TEST BAG

Reject Due To

No specimen should be rejected.

Reference Values


Reference values apply to all ages.

Day(s) Performed

Monday through Friday, Sunday

Report Available

Same day/1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
UBT H. pylori C Urea Breath Test 29891-9


Result ID Test Result Name Result LOINC Value
81590 H. pylori C Urea Breath Test 29891-9