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Test Code TFPSA Prostate-Specific Antigen (PSA), Total and Free, Serum or Plasma

Methodology

Dual Monoclonal Chemiluminescent Immunoassay

Specimen Requirements

Container/Tube:

Preferred: Lithium heparin (light green-top)

Acceptable: Serum Gel

 Draw blood, spin down within 2 hours of draw and send 1 mL (pediatric:  0.2 mL) of plasma or serum.
Note:  Include patient’s age on request form.

Specimen Stability Information

 

Specimen Type

Temperature

Time

Plasma,lithium heparin / Serum

RT, spun

8 hrs
  Refrigerated, spun 3 days

 

Reference Values

TOTAL PSA
0-59 years:  <3.9 ng/mL
60-70 years:  <5.4 ng/mL
>70 years:  <6.2 ng/mL
FREE PSA (FPSA)
Probability of finding prostate adenocarcinoma (PCA) on needle biopsy when Total PSA is 4-10 ng/mL: 

 

 % FPSA Ratio 50-59 years   60-69 years  >69 years
       
≤10 49.2 57.5 64.5 
11-18  26.9  33.9  40.8 
19-25  18.3  23.9  29.7 
 >25 9.1 12.2  15.8 

 

Reject Due To

 

 

 

Hemolysis

Mild:

ok

Gross:

ok

Lipemia

Mild:

ok

Gross:

ok

Icterus

Mild:

ok

Gross:

ok

 

Day(s) Test Set Up

Monday through Sunday

CPT Coding

84153 - total PSA
84154 - free PSA

Secondary ID

HHA1446

Performing Laboratory

Huntsville Hospital Laboratory

LOINC Coding

 

Test Name LOINC Code
Prostate Specific Ag

2857-1
Prostate Specific Ag. free 10886-0