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Test Code SUBIF IGG Subtypes Immunofluorescence, (IGG1, IGG2, IGG3, IGG4), Tissue

Advisory Information

This test will report as Negative to 3+.


If additional interpretation/analysis is needed, request PATHC/ Pathology Consultation along with this test and send the corresponding renal pathology light microscopy and immunofluorescence (IF) slides (or IF images on a CD), electron microscopy images (prints or CD), and the pathology report.

Shipping Instructions

1. Advise shipping specimens in Styrofoam transportation coolers to avoid extreme hot or cold temperatures to ensure specimens are received at required specimen stability temperature.

2. Attach the green pathology address label included in the kit to the outside of the transport container.

Necessary Information

A pathology/diagnostic report is required.

Specimen Required

Supplies: Renal Biopsy Kit (T231)

Specimen Type: Kidney tissue

Container/Tube: Renal Biopsy Kit, Zeus/Michel's, Frozen

Preferred: Frozen

Acceptable: 4 frozen tissue unstained positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.

Specimen Volume: Entire specimen

Collection Instructions: Collect specimens according to the instructions in Renal Biopsy-Procedures of Handling Tissue for Light Microscopy, Immunohistology, and Electron Microscopy in Special Instructions.

Additional Information: If standard immunoglobulin and complement immunofluorescence has already been performed, submit the residual frozen tissue (must contain glomeruli) on dry ice.


Renal Biopsy Patient Information in Special Instructions

Useful For

Determining the subclass of IgG antibody found in renal immunofluorescent panel and determining if the deposits are monoclonal or monotypic

Method Name

Direct Immunofluorescence on Fresh/Frozen Tissue

Reporting Name

IGG Subtypes Immunofluorescence

Specimen Type


Specimen Stability Information

Specimen Type Temperature Time
Special Frozen (preferred)

Reject Due To


Cold OK; Warm OK, send note to lab

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Day(s) and Time(s) Performed

Monday through Friday

Analytic Time

Turnaround time is 1 working day (from receipt)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test uses a standard method. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

88346-primary IF

88350-if additional IF

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SUBIF IGG Subtypes Immunofluorescence In Process


Result ID Test Result Name Result LOINC Value
BA0271 Interpretation 50595-8
BA0272 Participated in the Interpretation No LOINC Needed
BA0275 Report electronically signed by 19139-5
BA0276 Addendum 35265-8
BA0274 Gross Description 22634-0
BA0273 Material Received 22633-2
71618 Disclaimer 62364-5
71850 Case Number 80398-1