Test Code RZIKS Zika Virus, PCR, Molecular Detection, Serum
Ordering Guidance
Due to similar clinical presentations, testing for RNA or IgM-class antibodies to dengue and chikungunya viruses, concurrently with Zika virus testing, is strongly recommended.
Necessary Information
Order questions and answers concerning pregnancy, exposure, and display of symptoms are required.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container: Sterile container
Specimen Volume: 0.5 mL
Collection Instructions:
1. Collect whole blood in a serum gel tube.
2. Centrifuge and aliquot the serum into a sterile container within 6 hours of collection.
3. Label specimen as serum.
Useful For
Qualitative detection of Zika virus RNA in serum from individuals meeting CDC Zika virus clinical or epidemiologic criteria
Testing Algorithm
The following algorithms are available in Special Instructions:
Special Instructions
Method Name
Real-Time Reverse Transcription Polymerase Chain Reaction (PCR)/DNA Probe Hybridization
Reporting Name
Zika Virus, PCR, SerumSpecimen Type
SerumSpecimen Minimum Volume
0.25 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 7 days | |
Frozen | 7 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Reference Values
Negative
Day(s) Performed
Tuesday, Thursday
Report Available
5 to 8 daysPerforming Laboratory

Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
87662
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
RZIKS | Zika Virus, PCR, Serum | 85622-9 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
47956 | Zika Serum PCR Result | 85622-9 |
PREGY | Is patient pregnant? | 11449-6 |
EXPOS | Has patient had Zika exposure? | 88636-6 |
SYMP | Has patient been symptomatic? | 75325-1 |
48059 | Zika Serum PCR Interpretation | 69048-7 |
Forms
If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.