Sign in →

Test Code RZIKS Zika Virus, PCR, Molecular Detection, Serum

Ordering Guidance

Due to similar clinical presentations, testing for RNA or IgM-class antibodies to dengue and chikungunya viruses, concurrently with Zika virus testing, is strongly recommended.

Necessary Information

Order questions and answers concerning pregnancy, exposure, and display of symptoms are required.

Specimen Required

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container: Sterile container

Specimen Volume: 0.5 mL

Collection Instructions:

1. Collect whole blood in a serum gel tube.

2. Centrifuge and aliquot the serum into a sterile container within 6 hours of collection.

3. Label specimen as serum.

Useful For

Qualitative detection of Zika virus RNA in serum from individuals meeting CDC Zika virus clinical or epidemiologic criteria

Testing Algorithm

The following algorithms are available in Special Instructions:

-Assessment for Zika Virus Infection

-Mosquito-borne Disease Laboratory Testing

Method Name

Real-Time Reverse Transcription Polymerase Chain Reaction (PCR)/DNA Probe Hybridization

Reporting Name

Zika Virus, PCR, Serum

Specimen Type


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  7 days

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values


Day(s) Performed

Tuesday, Thursday

Report Available

5 to 8 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
RZIKS Zika Virus, PCR, Serum 85622-9


Result ID Test Result Name Result LOINC Value
47956 Zika Serum PCR Result 85622-9
PREGY Is patient pregnant? 11449-6
EXPOS Has patient had Zika exposure? 88636-6
SYMP Has patient been symptomatic? 75325-1
48059 Zika Serum PCR Interpretation 69048-7


If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.