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Test Code RPRT Rapid Plasma Reagin (RPR), Response to Therapy, Serum

Advisory Information

This test is not intended for medical-legal use.


This test is for monitoring response to therapy in patients treated for syphilis infection. This test should not be used as a primary diagnostic approach for syphilis.


To screen for undiagnosed syphilis infection, order SYPGR / Syphilis IgG Antibody with Reflex, Serum.

Specimen Required


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL

Useful For

Determining the current disease status and evaluating response to therapy for syphilis

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
RRPRQ RPR Titer, S No No

Testing Algorithm

If this test is positive, RPR titer will be performed at an additional charge.

Method Name


Reporting Name

RPR, Response to Therapy, S

Specimen Type


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To


Mild OK; Gross reject


Mild OK; Gross reject





Reference Values


Day(s) and Time(s) Performed

Monday through Saturday; 8 a.m.

Analytic Time

Same day/1 day

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
RPRT RPR, Response to Therapy, S 31147-2


Result ID Test Result Name Result LOINC Value
31696 RPR, Response to Therapy, S 31147-2