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Test Code PLAVIX P2Y12 Assay (Plavix), Blood

Important Note

  • Difficulty in specimen collection may result in spurious values.
  • Patients with inherited platelet disorders such a Von Willebrand Factor Deficiency, Glazmann Thrombasthenia and Bernard-Soulier Syndrome have not been studied with the VerifyNow PRU (P2Y12) Test. This test is not intended for use with these types of platelet disorders.
  •  Patients who have been treated with Glycoprotein IIb/IIIa inhibitor drugs should not be tested until platelet function has recovered. This time period is approximately 14 days after discontinuation of ReoPro and up to 48 hours for Integrilin and Aggrastat. The platelet function recovery time varies among individuals and is longer for patients with renal dysfunction.  

Methodology

Turbidimetric

Includes platelet function P2Y12 reaction units (PRU), platelet function base PRU, and P2Y12 inhibition %.

Specimen Requirements

Do not transport specimen in pneumatic tube. Specimen must be hand delivered to laboratory, and test must be analyzed within 4 hours of draw.

 

Draw blood using a 21 gauge needle, first into 1 clear BD discard tube followed by 2 Greiner Bio-One vacuette tubes. Allow tubes to fill to the black line. Do not over or under fill tubes. Gently invert the tubes 5 times to ensure adequate mixing. Do not shake tubes. Forward unprocessed whole blood promptly at ambient temperature only.

Specimen Stability Information

 

Specimen Type

Temperature

Time

Whole blood, Greiner Bio-One vacuette tubes

RT

4 hrs

 

Day(s) Test Set Up

Monday through Sunday

CPT Coding

85576

Secondary ID

HHA1514

Performing Laboratory

Huntsville Hospital Laboratory