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Test Code LD_I Lactate Dehydrogenase (LDH) Isoenzymes, Serum


Necessary Information


Patient's age is required.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL divided into 2 containers each containing 1 mL

Collection Instructions: Centrifuge and aliquot serum into 2 plastic vials, each containing 1 mL, within 2 hours of collection.


Useful For

Investigating a variety of diseases involving the heart, liver, muscle, kidney, lung, and blood

 

Differentiating heart-synthesized lactate dehydrogenase (LDH) from liver and other sources

 

Investigating unexplained causes of LDH elevations

 

Detection of macro-LDH

Profile Information

Test ID Reporting Name Available Separately Always Performed
LD Lactate Dehydrogenase (LD), S Yes Yes
LDI LD Isoenzymes, S No Yes

Method Name

LDI: Electrophoresis Densitometry

LD: Photometric Rate Reaction

Reporting Name

Lactate Dehydrogenase Isoenzymes, S

Specimen Type

Serum

Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Ambient (preferred) 7 days
  Refrigerated  48 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Reference Values

LACTATE DEHYDROGENASE (LD)

1-30 days: 135-750 U/L

31 days-11 months: 180-435 U/L

1-3 years: 160-370 U/L

4-6 years: 145-345 U/L

7-9 years: 143-290 U/L

10-12 years: 120-293 U/L

13-15 years: 110-283 U/L

16-17 years: 105-233 U/L

≥18 years: 122-222 U/L

 

LD ISOENZYMES

I (fast band): 17.5-28.3%

II: 30.4-36.4%

III: 19.2-24.8%

IV: 9.6-15.6%

V (slow band): 5.5-12.7%

Day(s) Performed

Monday, Wednesday, Friday

Report Available

3 to 6 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83615

83625

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LD_I Lactate Dehydrogenase Isoenzymes, S 42929-0

 

Result ID Test Result Name Result LOINC Value
LD Lactate Dehydrogenase (LD), S 14804-9
305 LD Isoenzymes, S 49279-3
3344 Total LD Activity 14804-9
2282 I, Heart 2536-1
2283 II 2539-5
2285 III 2542-9
2286 IV 2545-2
2287 V, Liver 2548-6