Test Code I2SW Iduronate-2-Sulfatase, Blood
Necessary Information
Provide a reason for testing with each specimen.
Specimen Required
Container/Tube:
Preferred: Lavender top (EDTA)
Acceptable: Yellow top (ACD)
Specimen Volume: 2 mL
Forms
1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available:
-Informed Consent for Genetic Testing (T576)
-Informed Consent for Genetic Testing-Spanish (T826)
2. Biochemical Genetics Patient Information (T602)
3. If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.
Useful For
Diagnosis of mucopolysaccharidosis II (MPS II, Hunter syndrome) in whole blood specimens
This test is not useful for determining carrier status for MPS II.
Special Instructions
Method Name
Fluorometric Enzyme Assay
Reporting Name
Iduronate-2-sulfatase, BSpecimen Type
Whole bloodSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole blood | Ambient (preferred) | 7 days | |
Refrigerated | 7 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
≥1.5 nmol/hour/mL
Day(s) Performed
Varies
Report Available
8 to 15 daysPerforming Laboratory

Test Classification
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82657
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
I2SW | Iduronate-2-sulfatase, B | 79462-8 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
61902 | Iduronate-2-sulfatase, B | 79462-8 |
35211 | Reviewed By | 18771-6 |
35212 | Interpretation (I2SW) | 59462-2 |
Testing Algorithm
The following algorithms are available: