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HelpTest Code GM1B Ganglioside Antibody Panel, Serum
Specimen Required
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 1 mL
Forms
If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/neurology-request-form.pdf)
Useful For
Supporting diagnosis of neurological diseases-primarily motor neuron disease and motor neuropathies
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| IGG_M | IgG Monos. GM1 | No | Yes |
| IGM_M | IgM Monos. GM1 | No | Yes |
| IGG_A | IgG Asialo. GM1 | No | Yes |
| IGM_A | IgM Asialo. GM1 | No | Yes |
| IGG_D | IgG Disialo. GD1b | No | Yes |
| IGM_D | IgM Disialo. GD1b | No | Yes |
Method Name
Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
Ganglioside Ab Panel, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen (preferred) | 14 days |
| Refrigerated | 14 days |
Reject Due To
|
Hemolysis |
Mild OK; Gross reject |
|
Lipemia |
Mild OK; Gross reject |
|
Icterus |
Mild OK; Gross OK |
|
Other |
NA |
Reference Values
99% of Normals Fall at or Below This Titer
|
IgG monosialo GM1 |
1:500 |
|
IgM monosialo GM1 |
1:1,000 |
|
IgG asialo GM1 |
1:4,000 |
|
IgM asialo GM1 |
1:4,000 |
|
IgG disialo GD1b |
1:1,000 |
|
IgM disialo GD1b |
1:1,000 |
Borderline Ranges
|
IgG monosialo GM1 |
=1:1,000 |
|
IgM monosialo GM1 |
=1:2,000 |
|
IgG asialo GM1 |
=1:8,000 |
|
IgM asialo GM1 |
No borderline range (normal: ≤4,000) |
|
IgG disialo GD1b |
No borderline range (normal: ≤1,000) |
|
IgM disialo GD1b |
No borderline range (normal: ≤1,000) |
Abnormal Results
|
IgG monosialo GM1 |
>1:1,000 |
|
IgM monosialo GM1 |
>1:2,000 |
|
IgG asialo GM1 |
>1:8,000 |
|
IgM asialo GM1 |
>1:4,000 |
|
IgG disialo GD1b |
>1:1,000 |
|
IgM disialo GD1b |
>1:1,000 |
Day(s) and Time(s) Performed
Tuesday, Thursday; 3 p.m.
Analytic Time
3 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
83516 x 6
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| GM1B | Ganglioside Ab Panel, S | 82455-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 4414 | IgG Asialo. GM1 | 46969-2 |
| 4416 | IgG Disialo. GD1b | 13662-2 |
| 4412 | IgG Monos. GM1 | 43240-1 |
| 4415 | IgM Asialo. GM1 | 43179-1 |
| 4417 | IgM Disialo. GD1b | 13661-4 |
| 4413 | IgM Monos. GM1 | 43241-9 |
| 4418 | Comment | 48767-8 |