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Test Code F2ISO F2-Isoprostanes, Random, Urine

Specimen Required

Patient Preparation: Patient should not take nonsteroidal anti-inflammatory drugs within the 72 hours or aspirin within the 2 weeks prior to specimen collection.

Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Container/Tube: Plastic urine tube

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.


If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.

Useful For

Assessment of in vivo lipid peroxidation


Considered to be an index of systemic oxidative stress over time

Additional Tests

Test ID Reporting Name Available Separately Always Performed
CRETR Creatinine, Random, U No Yes

Testing Algorithm

When F2-isoprostanes testing is performed, urine creatinine will always be performed at an additional charge.

Method Name

F2ISO: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

CRETR: Enzymatic Colorimetric Assay

Reporting Name

F2-Isoprostanes, U

Specimen Type


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days
  Frozen  30 days
  Ambient  7 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

≥18 years: ≤1.0 ng/mg creatinine

Reference values have not been established for patients who are younger than 18 years of age

Day(s) Performed


Report Available

2 to 9 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
F2ISO F2-Isoprostanes, U 90783-2


Result ID Test Result Name Result LOINC Value
88677 15-F2t-Isoprostane, U 90783-2