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Test Code CKCKMB Creatine Kinase (CK) MB Isoenzyme, Serum or Plasma

Methodology

CK:  Kinetic Reaction

MB:  Electrochemiluminescence Immunoassay (ECLIA)
Note:  Includes CK, total and isoenzymes. 

Specimen Requirements

Container/Tube:

Preferred: Lithium heparin (light green-top)

Acceptable: Serum Gel

 Draw blood, spin down and send 1 mL (pediatric:  0.2 mL) of plasma or serum.

Note:  Include date and time of draw on request form.

Specimen Stability Information

 

Specimen Type

Temperature

Time

Plasma,lithium heparin / Serum

RT, spun

 5 hrs
 

Refrigerated,  spun

 12 hrs

 

Reference Values

 

TOTAL CK
Age Male (IU/L) Female (IU/L)
0-11 months 2-129 2-146
1-6 years 2-163 2-134
7-12 years 2-217 26-145
13-15 years 2-251 2-143
16-17 years 2-238 13-144
>17 years 38-174 26-140

Note:  A positive CKMB on Reference Lab Patients will be treated as a critical value.
Note:  Strenuous exercise or intramuscular injections may cause transient elevation of CK.

 

ISOENZYMES
MB:  <5.0 ng/mL


RELATIVE INDEX:  <2.5
The relative index represents the ratio of CK-MB to the CK, total. Relative index = (CK-MB, in ng/mL ÷ CK, total, U/L) x 100. Due to the different units measured (ng/mL for CK-MB vs. U/L for CK, total), this does not represent a true percentage and is, therefore, called a “relative index.” Currently, a relative index of ≥2.5 suggests the MB may be myocardial in origin. The relative index may be of particular value in patients who have elevated CK, total due to trauma or surgery.

Reject Due To

 

Hemolysis

Mild:

Reject

Gross:

Reject

Lipemia

Mild:

ok

Gross:

ok

Icterus

Mild:

ok

Gross:

ok

 

Day(s) Test Set Up

Monday through Sunday

CPT Coding

82550 - CK, total
82553 - CK isoenzyme

Secondary ID

HHA1421

Performing Laboratory

Hunstville Hospital Laboratory/Madison Hospital Laboratory