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Test Code CASF IgG/Albumin Ratio, Spinal Fluid


Advisory Information


The cerebrospinal fluid (CSF) index in which the CSF IgG/albumin ratio is compared to the serum IgG/albumin ratio aids in the diagnosis of individuals with multiple sclerosis. See SFIN / Cerebrospinal Fluid (CSF) IgG Index, Serum and Spinal Fluid.



Specimen Required


Collection Container/Tube: Sterile vial

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL


Useful For

Assessment of cerebrospinal fluid (CSF) IgG/albumin ratio in the absence of a paired CSF and serum specimen

Method Name

Nephelometry

Reporting Name

IgG/Albumin Ratio, CSF

Specimen Type

CSF

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross OK

Other

NA

Reference Values

CSF IgG: 0.0-8.1 mg/dL

CSF albumin: 0.0-27.0 mg/dL

CSF IgG/albumin: 0.00-0.21

Day(s) and Time(s) Performed

Monday through Saturday; 2 p.m.

Analytic Time

Same day/1 day

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

82042

82784

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CASF IgG/Albumin Ratio, CSF 2470-3

 

Result ID Test Result Name Result LOINC Value
IGG_C IgG, CSF 2464-6
ALB_C Albumin, CSF 1746-7
AIGAC IgG/Albumin, CSF 2470-3